Premium
Postirradiation sarcoma (malignant fibrous histiocytoma) following breast carcinoma. An ultrastructural study of a case
Author(s) -
Tsuneyoshi Masazumi,
Enjoji Munetomo
Publication year - 1980
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(19800315)45:6<1419::aid-cncr2820450620>3.0.co;2-m
Subject(s) - ultrastructure , medicine , pathology , sarcoma , soft tissue , breast carcinoma , radiation therapy , carcinoma , radiology , breast cancer , cancer
Sarcoma of the chest wall following postoperative radiation therapy (2500 rads) for breast carcinoma is presented; it appeared 16 years after the initial radiation, and had light and electron microscopic features of malignant fibrous histiocytoma (MFH). Unique ultrastructural finding was the presence of Langerhans cell granules in some of the tumor cells. This appears to be the first documented instance of a soft tissue MFH containing such granules in the tumor cells.