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Favorable outcome of central nervous system toxoplasmosis occurring in a patient with untreated Hodgkin's disease
Author(s) -
Green Jon A.,
Spruance Spotswood L.,
Cheson Bruce D.
Publication year - 1980
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(19800215)45:4<808::aid-cncr2820450433>3.0.co;2-c
Subject(s) - toxoplasmosis , medicine , lymphoma , disease , central nervous system , toxoplasma gondii , pathology , immunology , antibody
The current report describes severe, multi‐focal central nervous system (CNS) toxoplasmosis in a patient with untreated Hodgkin's disease. Anti‐toxoplasma therapy was associated with prompt clinical improvement, and as such may represent the first successfully treated case of global CNS‐toxoplasmosis occurring in a person with histologically documented lymphoma. Previously, CNS‐toxoplasmosis has been noted to complicate lymphomas after initiation of anti‐neoplastic therapy. The occurrence of disseminated toxoplasmosis prior to anti‐neoplastic therapy is unique and suggests that lymphoma per se is a predisposing factor. Cancer 45:808‐810, 1980.