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Urinary hexosaminidase in patients with lung carcinoma
Author(s) -
Brattain M. G.,
Kimball P. M.,
Durant J. R.,
Pretlow T. G.,
Smith D.,
Carpenter J.,
Marks M.
Publication year - 1979
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(197912)44:6<2267::aid-cncr2820440640>3.0.co;2-m
Subject(s) - medicine , hexosaminidase , urinary system , lung , carcinoma , disease , population , gastroenterology , pathology , enzyme , biochemistry , biology , environmental health
The specific activity of urinary hexosaminidase was determined in 58 patients with various histological types of lung carcinoma. Compared to an apparently healthy control population, 32/35 patients with widely disseminated disease showed elevated values and 18/23 patients with disease confined to the chest had normal hexosaminidase values. Detailed studies of 18 patients indicated that declining hexosaminidase values were associated with effective therapy, rising values generally accompanied progressive disease.