Premium
Evaluation of fast neutron teletherapy for advanced carcinomas of the major salivary glands
Author(s) -
Henry Larry W.,
Blasko John C.,
Griffin Thomas W.,
Parker Robert G.
Publication year - 1979
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(197909)44:3<814::aid-cncr2820440304>3.0.co;2-u
Subject(s) - medicine , parotid gland , salivary gland , nuclear medicine , neutron , radiology , pathology , quantum mechanics , physics
This review analyzes the local control rate of fast neutron beam teletherapy for malignant salivary gland carcinomas compared to conventional photon irradiation at the same institution. Thirty patients with malignant parotid or submaxillary gland tumors were treated with either cobalt‐60 (19 patients) or neutrons ± photons (11 patients). The 19 photon‐treated patients were historical controls. No advantage is found for neutrons in patients with tumors less than 3 cm where 100% local control was achieved with either modality. In patients with tumor masses 3–6 cm in size, neutrons demonstrated a possible advantage with a local control rate of 100% (followup, 7–18 months) compared to a control rate of 33% with conventional photon irradiation. Acute treatment‐related morbidity was slightly greater in neutron‐treated patients, but no long‐term complications have been observed to date.