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Metastasizing extradural ependymoma of the sacrococcygeal region. Case report and review of literature
Author(s) -
Vagaiwala Minoo R.,
Robinson Joe S.,
Galicich Joseph H.,
Gralla Richard J.,
Helson Lawrence,
Beattie Edward J.
Publication year - 1979
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(197907)44:1<326::aid-cncr2820440156>3.0.co;2-4
Subject(s) - medicine , ependymoma , primary tumor , metastasis , transplantation , surgery , radiology , cancer
A case is discussed in which the patient presented with a primary extradural sacrococcygeal ependymoma and synchronous pulmonary metastasis. The clinical course has been characterized by recurrent pulmonary metastases. Management has consisted of repeated surgical resections of the pulmonary metastases and the tumor at the primary site; and the use of a wide spectrum of chemotherapeutic agents. Transplantation of this tumor into nude mice initially resulted in rapid growth but there was spontaneous regression in the second transplants. A general discussion of the management of such lesions is presented, and the literature pertaining to this tumor is discussed.