Premium
A new characteristic karyotypic anomaly in lymphoproliferative disorders
Author(s) -
Van Den Berghe H.,
Parloir C.,
David G.,
Michaux J. L.,
Sokal G.
Publication year - 1979
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(197907)44:1<188::aid-cncr2820440131>3.0.co;2-f
Subject(s) - medicine , anomaly (physics) , lymphoproliferative disorders , pathology , lymphoma , physics , condensed matter physics
A new characteristic chromosome anomaly t(11;14)(q14;q32?) in lymphoproliferative disorders (LPD) is described in 4 cases. The extra material was found on a #14 chromosome (14q+) and belonged to the long arm of one #11 chromosome in 3 cases and to the long arm of a #14 in the other case. These cases confirm that the distal end of chromosome 14q may function as a “receptor site,”according to the hypothesis of Kaiser‐McCaw et al. 12 and also tend to indicate that chromosome #14 may not be unique in showing so‐called “donor” and “receptor sites,”and that other chromosomes, in casu chromosome #11, may behave similarly.