Premium
Latent thyroid carcinoma at autopsy: A study from Oporto, Portugal
Author(s) -
SobrinhoSimões Manuel A.,
Sambade Maria C.,
Gonçalves Vicente
Publication year - 1979
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(197905)43:5<1702::aid-cncr2820430521>3.0.co;2-s
Subject(s) - medicine , thyroid , autopsy , pathology , thyroid carcinoma , carcinoma , cervical lymph nodes , cancer , metastasis
Thirty‐nine (6.5%)latent thyroid carcinomas were found in 600 thyroid glands removed at autopsy in Oporto Medical School Laboratory of Pathology. The prevalence of latent thyroid carcinomas was significantly higher in women (sex ratio 4.3:1) and in elderly people (p < 0.005) and appeared to be independent from the existence of another malignant neoplasm. The mean thyroid weight and the concurrent thyroid pathology of patients with thyroid carcinomas were not significantly different from those of patients without them. The study of cervical lymph nodes in the first 400 autopsies did not show any significant difference concerning histologic pattern, number of germinal centers and sinus histiocytosis between patients with thyroid carcinomas and those without them. Further investigation is required to evaluate the role of host factors on the peculiar characteristics of latent thyroid carcinomas.