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A nonfunctioning paraganglioma of vagus nerve: An ultrastructural study
Author(s) -
Chaudhry Anand P.,
Haar Jean G.,
Koul Ashok,
Nickerson Peter A.
Publication year - 1979
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(197905)43:5<1689::aid-cncr2820430520>3.0.co;2-5
Subject(s) - ultrastructure , vagus nerve , paraganglioma , axon , anatomy , medicine , pathology , nerve cells , biology , microbiology and biotechnology , stimulation
The clinical, histological, and ultrastructural aspects of a cervical paraganglioma of the vagus nerve, in a 66‐year‐old white man, have been discussed in detail. Ultrastructurally, the tumor chief cells contained characteristic membrane‐bound and dense‐cored neurosecretory granules which ranged in size from 85 mμ to 190 mμ Unlike earlier ultrastructural reports, the present study showed the presence of sustentacular or supporting cells. These cells were smaller, darker, polymorphic, and were commonly located at the periphery of a single or group of chief cells. Furthermore, unlike earlier reports on vagal paragangliomas, nonmyelinated nerve fibers and an occasional axon were identified in the present fine structure study.