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Extragenital adenomatoid tumor: Evidence for the mesothelial theory of origin
Author(s) -
Craig John R.,
Hart William R.
Publication year - 1979
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(197905)43:5<1678::aid-cncr2820430518>3.0.co;2-n
Subject(s) - adenomatoid tumor , histogenesis , mesothelioma , pathology , medicine , mesothelium , mesothelial cell , immunohistochemistry
The histogenesis of so‐called adenomatoid tumors has been contested. Doubts as to a mesothelial derivation often have been based on the belief that adenomatoid tumors originate exclusively in or nearby genital tract organs. This report documents a histologically typical adenomatoid tumor which developed in the mesentery of the small intestine. Extensive clinical investigations and an uneventful 3‐year postoperative follow‐up interval confirmed that the tumor was not a metastatic adenocarcinoma or malignant mesothelioma. The extra‐genital site of origin of this neoplasm provides additional corroborative evidence for the mesothelial origin of adenomatoid tumors. Regardless of their anatomic location, these distinctive neoplasms should be classified as benign adenomatoid mesotheliomas.