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Small cell tumor of cervix with neuroepithelial features. Ultrastructural observations in two cases
Author(s) -
Mackay Bruce,
Osborne Barbara M.,
Wharton J. Taylor
Publication year - 1979
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(197903)43:3<1138::aid-cncr2820430353>3.0.co;2-u
Subject(s) - neuroepithelial cell , medicine , pathology , cervix , neural crest , metastasis , ultrastructure , cell , pancreas , basal cell , carcinoma , cancer , biology , stem cell , embryo , genetics , neural stem cell , microbiology and biotechnology
Two cases of small cell tumor of the uterine cervix are reported in which electron microscopic studies indicated that the tumor cells were of neural crest origin. Both tumors behaved aggressively, and metastatic involvement of pancreas was demonstrated in one patient, while the second patient developed liver metastasis. The need to distinguish these neoplasms from squamous cell carcinoma of the cervix is stressed. The tumors are compared with small cell neuroepithelial neoplasms previously reported as adult neuroblastomas. Cancer 43:1138–1145, 1979.