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Tumors of the pineal and suprasellar region: Childrens cancer study group treatment results 1960–1975. A report from childrens cancer study group
Author(s) -
Wara William M.,
Jenkin Derek T.,
Evans Audrey,
Ertel Inta,
Hittle Robert,
Ortega Jorge,
Wilson Charles B.,
Hammond Denman
Publication year - 1979
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(197902)43:2<698::aid-cncr2820430243>3.0.co;2-y
Subject(s) - medicine , germinoma , radiation therapy , cancer , biopsy , surgery , radiology
Tumors of the pineal and suprasellar region form a rare and interesting group of lesions with germinomas accounting for over 50% of all lesions in this anatomic region. The Brain Tumor Committee of Childrens Cancer Study Group (CCSG) recently surveyed all CCSG member institutions to determine treatment parameters and assess the techniques. A total of 140 patients were seen during the period from 1960 to 1975; 118 patients were evaluable, having adequate treatment records. One hundred and one patients were less than 30 years of age with a 2:1 male predominance. Thirty‐six of the 57 biopsied patients (63%) were found to have germinomas. The survival of patients in the germinoma group (72%) was comparable to that of the patients without biopsy (71%). The overall survival rate for all patients (biopsied and unbiopsied) was 65% with follow‐up times ranging from 2 to 15 years. Nine patients developed spinal cord metastases (8%), two of whom also had simultaneous primary recurrence; none of these patients had received adjunctive spinal irradiation. Cancer 43:698–701, 1979.