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Multiple pulmonary lesions in a patient treated with BCNU (1,3‐BIS(2‐chloroethyl)‐1‐nitrosourea) for glioblastoma multiforme
Author(s) -
Bellot Peter A.,
Valdiserri Ronald O.
Publication year - 1979
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(197901)43:1<46::aid-cncr2820430106>3.0.co;2-c
Subject(s) - medicine , nitrosourea , carmustine , glioblastoma , pathology , hyperplasia , chemotherapy , cancer research , etoposide
Abstract A patient with a glioblastoma multiforme who was treated with BCNU, developed rapidly progressive pulmonary disease. The pulmonary changes were studied pathologically and included atypical alveolar cell hyperplasia, hyaline membranes, and interstitial fibrosis. These lesions contributed to the patient's demise and may be related to the administration of BCNU.