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The candida precipitin test in an immunosuppressed population
Author(s) -
Guinan Mary E.,
Portas Mary R.,
Hill Harry R.
Publication year - 1979
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(197901)43:1<299::aid-cncr2820430143>3.0.co;2-d
Subject(s) - precipitin , counterimmunoelectrophoresis , medicine , immunology , population , antibody , environmental health
Ninety‐one immunosuppressed, high‐risk patients suspected of having invasive candidiasis were tested during their septic episode for the presence of candida precipitin (CP) antibody using the counterimmunoelectrophoresis (CIE) method. In 12 patients, systemic candidiasis was confirmed but only 6 of these (50%) had candida precipitins. In 14 “questionable” cases who died without a definitive diagnosis, 8 (57%) had precipitin antibody. Of the 65 patients who did not have serious candida infection, 20 (31 %) had candida precipitins. In this population we found the presence of candida precipitins to be neither sensitive (50%) nor specific (69%) for the diagnosis of invasive candidiasis.