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Late onset chronic mucocutaneous candidiasis with lymphoma and specific serum inhibitory factor
Author(s) -
Aronson Iris K.,
Rieger Christian H. L.,
Soltani Keyoumars,
Tkalcevic Vladimir,
Chan Wing C.,
Lorincz Allan L.,
Matz Gregory
Publication year - 1979
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(197901)43:1<101::aid-cncr2820430116>3.0.co;2-6
Subject(s) - medicine , chronic mucocutaneous candidiasis , mucocutaneous zone , lymphoma , immunostimulant , immunology , amphotericin b , immune system , dermatology , disease , antifungal
A patient with late onset chronic mucocutaneous candidiasis developed lymphocytic lymphoma. A specific inhibitor of in vitro lymphoproliferative responses to candidal antigen was detected in her serum which persisted following clinical remission of candidiasis after combined amphotericin‐B and 5‐Fluorocystosine therapy. It is unclear whether the combined therapy was exclusively anticandidal, nonspecific immunostimulant or cytotoxic affecting the underlying incipient lymphoma.