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Immunological monitoring during chemotherapy for advanced Hodgkin's disease
Author(s) -
Alexopoulos C. G.,
Wiltshaw E.
Publication year - 1978
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(197812)42:6<2631::aid-cncr2820420619>3.0.co;2-i
Subject(s) - medicine , chemotherapy , in vivo , immunology , disease , candida albicans , antigen , immunologic tests , in vitro , pathology , biology , biochemistry , genetics , microbiology and biotechnology
A study of some immunologic in vitro and in vivo changes during the course of chemotherapy in 17 cases of advanced Hodgkin's disease was made. Skin testing with PPD, candida albicans and streptodornase antigens was studied together with studies of B and T cell numbers in the blood and responses to migration inhibition testing for PPD and PHA. An excellent correlation was found between recovery of normal immunologic responses and clinical remission despite the use of immunosuppressive chemotherapy. Cancer 42:2631–2640, 1978.