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Immunoblastic lymphadenopathy associated with methyldopa therapy. A case report
Author(s) -
Weisenburger Dennis D.
Publication year - 1978
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(197811)42:5<2322::aid-cncr2820420532>3.0.co;2-e
Subject(s) - medicine , discontinuation , rash , differential diagnosis , generalized lymphadenopathy , weakness , dermatology , surgery , lymphoma , pathology
The case of a 71‐year‐old woman who developed generalized weakness, lymphadenopathy, and a skin rash during methyldopa therapy is described. The prompt disappearance of symptoms following the discontinuation of the drug implicates it in the initial triggering of the abnormal lymphoid proliferation. Shortly thereafter, florid immunoblastic lymphadenopathy developed, and the patient subsequently responded to corticosteroid therapy. The frequent occurrence of immunoblastic lymphadenopathy during or shortly after the administration of various therapeutic medications is emphasized. The nature of the disorder and its differential diagnosis are discussed. Cancer 42:2322–2327, 1978.