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Immunotherapy with BCG administered by scarification. Standardization of reactions and management of side effects
Author(s) -
Hortobagyi G. N.,
Richman S. P.,
Dandridge K.,
Gutterman J. U.,
Blumenschein G. R.,
Hersh E. M.
Publication year - 1978
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(197811)42:5<2293::aid-cncr2820420529>3.0.co;2-o
Subject(s) - scarification , medicine , standardization , side effect (computer science) , administration (probate law) , immunotherapy , immunology , immune system , botany , germination , dormancy , political science , computer science , law , biology , programming language
The method of administering BCG by scarification is described in detail. A system of classifying the intensity of local reactions is proposed to standardize administration. The experience of the M. D. Anderson Hospital involving over 2700 patients is reviewed. Administration of BCG by scarification has been accomplished with safety and has been well tolerated and accepted. The most commonly observed side effects are discussed as well as their management. Cancer 42:2293–2303, 1978.