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Primary management of operable breast cancer by minimal surgery and radiotherapy
Author(s) -
Alpert S.,
Ghossein N. A.,
Stacey P.,
Migliorelli F. A.,
Efron G.,
Krishnaswamy V.
Publication year - 1978
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(197810)42:4<2054::aid-cncr2820420456>3.0.co;2-7
Subject(s) - medicine , radiation therapy , mastectomy , breast cancer , surgery , cancer , total mastectomy
109 cases of breast cancer were treated by tumorectomy and radiotherapy or radiotherapy alone. Almost 30% with small tumors (T1, T2) were considered inoperable for medical reasons and 70% refused mastectomy. Over the past five years the number of patients refusing mastectomy has definitely increased. 49 cases of surgically resectable cancers (T1, T2, T3, NO, N1) had a minimum followup of two years (average 4 years ± 3 months). Absolute and determinate survivals NED were 65% and 86%. There were four local recurrences (8%). Secondary mastectomy could be performed on three. Microscopic involvement of the surgical margin by cancer did not alter the local control rate. The cosmetic results were good in 98%. Gross removal of the tumor followed by radiotherapy may be offered as an alternative to mastectomy in patients with operable breast cancer. Cancer 42:2054–2058, 1978.