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Relative high frequency of childhood Hodgkin's disease in the north of Portugal
Author(s) -
SobrinhoSimões Manuel A.,
Areias Maria A.
Publication year - 1978
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(197810)42:4<1952::aid-cncr2820420438>3.0.co;2-k
Subject(s) - medicine , nodular sclerosis , disease , socioeconomic status , pediatrics , demography , pathology , lymphoma , hodgkin lymphoma , environmental health , population , sociology
Sex, age and histopathologic pattern of 322 cases of Hodgkin's disease diagnosed at the Laboratory of Pathology of Oporto Medical School between 1930 and 1974 are presented. 35 (10.9%) of the 322 patients were less than 10 years old. The male/female ratio of childhood Hodgkin's disease was 2.9:1 and the histologic observation revealed mixed cellularity in 18 (51.4%) and nodular sclerosis in 10 (28.6%) of the 35 cases. Childhood Hodgkin's disease relative frequency has abruptly decreased in the last five years of the study period. Most of the children belonged to large families living under poor socioeconomic conditions and the majority of them presented in advanced clinical stages. These findings are similar to those previously described in some developing countries of tropical and subtropical regions and reinforce the advanced relationship between under‐development and the geographic variations in childhood Hodgkin's disease frequency and pattern. Cancer 42:1952–1956, 1978.