Premium
A preliminary study of intralesional, intralymph node, intravenous and intraperitoneal Corynebacterium parvum treatments in patients with advanced cancer
Author(s) -
Cheng Vincent S. T.,
Suit Herman D.,
Wang C. C.,
Raker John,
Weymuller Ernest,
Kaufman Sheldon
Publication year - 1978
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(197810)42:4<1912::aid-cncr2820420432>3.0.co;2-5
Subject(s) - medicine , lymph node , basal cell , stage (stratigraphy) , soft tissue , oral cavity , surgery , carcinoma , dentistry , paleontology , biology
Twenty‐one patients with squamous cell carcinoma of oral cavity and/or cervical lymph node and four patients with soft tissue sarcomas were given intralesional (2–4 mg/m 2 ) and intralymph node (2–4 mg/m 2 ) C. parvum injections followed by 5 intravenous (2–4 mg/m 2 ) C. parvum treatments and conventional therapies. Seven patients with Stage III ovarian carcinomas were given intraperitoneal (2–4 mg/m 2 ) C. parvum injections followed by conventional therapies. The local and systemic effects of the C. parvum treatments were described and the anti‐tumor effects were evaluated in this series of patients. Cancer 42:1912–1915, 1978.