Premium
Initial levels of CEA and their rate of change in pancreatic carcinoma following surgery chemotherapy and radiation therapy
Author(s) -
Barkin J. S.,
Kalser M. H.,
Kaplan R.,
Redlhammer D.,
Heal A.
Publication year - 1978
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(197809)42:3+<1472::aid-cncr2820420817>3.0.co;2-w
Subject(s) - medicine , radiation therapy , chemotherapy , pancreatic carcinoma , carcinoma , jaundice , obstructive jaundice , oncology , gastroenterology , surgery , pancreatic cancer , cancer
CEA levels and their rate of change in 41 patients with pancreatic carcinoma following surgery, chemotherapy and radiation therapy were determined. Surgical resection, though not curative, was associated with a decrease in CEA level, with approximately half these levels returned to normal. No correlation with survival was noted. CEA levels are increased by obstructive jaundice. Radiation alone or in combination with 5‐Fluorouracil did not change CEA levels in patients with locally unresectable pancreatic carcinoma. CEA levels progressively increased in patients with widespread metastatic pancreatic carcinoma, who expired from their disease.