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Cancers among users of preparations containing vitamin A. A case‐control investigation
Author(s) -
Smith P. G.,
Jick Hershel
Publication year - 1978
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(197808)42:2<808::aid-cncr2820420255>3.0.co;2-v
Subject(s) - medicine , vitamin , control (management) , artificial intelligence , computer science
The frequency of regular use of Vitamin A preparations was compared among 800 newly diagnosed cancer patients and 3433 patients with certain nonmalignant conditions. Overall there was no convincing evidence that regular consumption of such preparations protected against the development of cancer (risk ratio 0.85). However, there was a suggestion of a negative association among men (risk ratio 0.54, p < 0.01) but not among women (risk ratio 1.11). The negative association among men did not increase with the period that such preparations had been regularly taken and was not greater for squamous cell tumors. The results of this study offer encouragement for further epidemiologic studies of the possible protective role of Vitamin A against cancer.