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The immunological classification of acute lymphoblastic leukemias
Author(s) -
Brouet J. C.,
Seligmann M.
Publication year - 1978
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(197808)42:2+<817::aid-cncr2820420703>3.0.co;2-2
Subject(s) - medicine , lymphoblastic leukemia , phenotype , leukemia , acute lymphocytic leukemia , immunology , oncology , gene , genetics , biology
The main methods used in order to assess the immunological markers on the blast cells from patients with acute lymphoblastic leukemia (ALL) are critically evaluated. The classification of ALL according to the phenotype of the leukemic cells and their presumed origin is reviewed. The correlations with clinical features and prognosis, as well as their possible therapeutic implications, are discussed.