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Sinus histiocytosis with massive lymphadenopathy and paraparesis: Remission with chemotherapy. A case report
Author(s) -
Haas Rainer J.,
Helmig Magdalena S. E.,
Prechtel Klaus
Publication year - 1978
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(197807)42:1<77::aid-cncr2820420112>3.0.co;2-6
Subject(s) - medicine , sinus histiocytosis with massive lymphadenopathy , lymph , rosai–dorfman disease , sinus (botany) , chemotherapy , surgery , disease , dermatology , pathology , botany , biology , genus
A case of sinus histiocytosis with massive lymphadenopathy (SHML) in which cranial nerve function was impaired is described. Severe paraparesis due to an epidural block at the C2 and C5‐T2 levels was also present. Treatment with cytotoxic agents resulted in a dramatic decrease in the size of the involved lymph nodes and disappearance of neurological symptomatology. A review of the literature revealed that, although the disease is benign in its clinical course, the process is not restricted to the lymph nodes. The case reported here is the second case in which the epidural space was affected.