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Incidental discovery at radical mastectomy of inapparent hodgkin's disease in long term survivors
Author(s) -
Miller G. Andrew,
Jarowski Charles I.,
Coleman Morton,
Cibull Michael L.,
Posteraro Anthony F.,
Weksler Arc E.
Publication year - 1978
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(197807)42:1<318::aid-cncr2820420148>3.0.co;2-7
Subject(s) - medicine , radical mastectomy , disease , radiation therapy , metastatic adenocarcinoma , adenocarcinoma , mastectomy , dermatology , surgery , breast cancer , oncology , cancer , pathology
Abstract Two long‐term survivors with nodular sclerosing Hodgkin's disease were found to have adenocarcinoma of the breast sixteen and twenty years after limited field radiotherapy. Examination of the axillary nodes at radical mastectomy showed both metastatic adenocarcinoma and clinically inapparent Hodgkin's disease. The occurrence of persistent but clinically inactive Hodgkin's disease as well as the development of secondary malignancies in this disease has important clinical ramifications. Skin testing and in vitro lymphocyte transformation studies in these two patients were also done.