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Synchronous malignant glandular Schwannomas in congenital neurofibromatosis
Author(s) -
Krumerman Martin S.,
Stingle Walter
Publication year - 1978
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(197806)41:6<2444::aid-cncr2820410652>3.0.co;2-o
Subject(s) - histogenesis , neurofibromatosis , medicine , pathology , schwannoma , pathological , anatomy , immunohistochemistry
An eight‐year‐old child with congenital neurofibromatosis developed rapidly growing synchronous malignant schwannomas in the neck and mediastinum. These tumors, displaying a biphasic pattern of spindle cell sarcoma admixed with mucinous epithelium, represent the eighth and ninth known examples of glandular schwannoma. The clinical and pathological features of this case are detailed and the histogenesis of the tumors discussed.