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Alpha‐fetoprotein and human chorionic gonadotropin in a patient with a primary intracranial germ cell tumor
Author(s) -
NørgaardPedersen B.,
Lindholm J.,
Albrechtsen R.,
Riishede J.,
Arends J.,
Diemer N. H.
Publication year - 1978
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(197806)41:6<2315::aid-cncr2820410633>3.0.co;2-q
Subject(s) - human chorionic gonadotropin , alpha fetoprotein , medicine , staining , germ cell tumors , gonadotropin , germ cell , pathology , germinoma , radiation therapy , hormone , biology , chemotherapy , biochemistry , hepatocellular carcinoma , gene
A 17 year old man with a primary intracranial germ cell tumor in the pituitary region is reported. Both serum alpha‐fetoprotein (AFP) and serum human chorionic gonadotropin (hCG) were found elevated preoperatively. Normal levels of serum AFP and hCG were found after operation and radiotherapy. By indirect immunofluorescence staining of the tumor tissue a slight staining for AFP was localized to the endodermal vesicles, whereas a more intensive staining for hCG could be identified in the giant cells.