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Norepinephrine‐producing tumors of bilateral breasts. A case report
Author(s) -
Kaneko Hiroshi,
Hōjō Haruto,
Ishikawa Shinobu,
Yamanouchi Haruo,
Sumida Toshiko,
Saito Ryoji
Publication year - 1978
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(197805)41:5<2002::aid-cncr2820410547>3.0.co;2-2
Subject(s) - medicine , norepinephrine , autopsy , pathology , biopsy , urine , paraganglioma , radiology , dopamine
There was a tumor in the left breast which was suspected to be carcinoid tumor at excisional biopsy. Autopsy revealed the same tumor in the right nipple. In the cells of the bilateral tumors a number of argylophil granules were diffusely demonstrated and the neurosecretory ones were verified electronmicroscopically. In the urine of the patient a moderate amount of norepinephrine was excreted. It was presumed that the norepinephrine might have been produced from the breasts. In the literature reviewed, the case of breast carcinoid has not been reported previously.

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