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Leukemic reticuloendotheliosis. Report of a case with peripheral blood remission on androgen therapy
Author(s) -
Lusch Charles J.,
Ramsey Harry E.,
Katayama Isao
Publication year - 1978
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(197805)41:5<1964::aid-cncr2820410541>3.0.co;2-j
Subject(s) - medicine , peripheral blood , splenectomy , androgen , complete remission , peripheral , spontaneous remission , gastroenterology , surgery , pathology , chemotherapy , spleen , hormone , alternative medicine
Leukemic reticuloendotheliosis (LRE) has been generally considered to be poorly responsive to therapy other than splenectomy. The patient presented below developed a complete peripheral blood remission after prolonged therapy with an androgen (oxymetholone). There is very little published experience with androgen therapy in LRE. The experience with this patient suggests that androgens may produce a clinical remission by inducing significant improvement in the peripheral blood in some patients with this disease.