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Monocyte function in patients with solid neoplasms during immunotherapy with Corynebacterium parvum
Author(s) -
Scheinberg Morton A.,
Masuda Aoi,
Maluf José A.,
Mendes Nelson F.
Publication year - 1978
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(197805)41:5<1761::aid-cncr2820410517>3.0.co;2-j
Subject(s) - medicine , immunotherapy , monocyte , immune system , receptor , function (biology) , immunology , cancer research , biology , evolutionary biology
The present studies were performed in order to evaluate monocyte function in patients with solid neoplasms before and after administration of C. parvum. The results demonstrate that monocytes from cancer patients display increased numbers of C3 and Fc receptor sites after administration of C. parvum. It is concluded that characterization of monocyte receptor activity may be helpful in monitoring the effects of immunotherapy in the immune system.