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Clear cell sarcoma with melanogenesis
Author(s) -
Boudreaux D.,
Waisman J.
Publication year - 1978
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(197804)41:4<1387::aid-cncr2820410424>3.0.co;2-q
Subject(s) - sarcoma , medicine , neoplasm , pathology , cell , biology , genetics
Abstract An example of clear cell sarcoma, from the great toe of a young woman having an otherwise classic history and appearance is described, and a malignant giant cell component is reported for the first time. Histochemical and electron microscopic studies clearly demonstrate melanogenesis. The controversy over tissue of origin of this uncommon neoplasm is discussed and evidence in support of neurectodermal derivation is presented.