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Chemotherapy of malignant hemangiopericytoma
Author(s) -
Wong Peter P.,
Yagoda Alan
Publication year - 1978
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(197804)41:4<1256::aid-cncr2820410406>3.0.co;2-v
Subject(s) - medicine , hemangiopericytoma , vincristine , methotrexate , chemotherapy , cyclophosphamide , osteosarcoma , oncology , pathology
Thirty‐nine chemotherapy trials in 16 patients with metastatic hemangiopericytoma treated at MSKCC and 33 trials from the literature are reviewed. Adriamycin, alone or in combination drug regimens, is the most effective agent, producing complete and partial remissions in 50% of cases. Other drugs which show some activity include vincristine, cyclophosphamide, actinomycin, methotrexate and DTIC. The available data indicate malignant hemangiopericytoma should be considered chemotherapeutically responsive tumors.