Premium
Adenocarcinoma of the stomach: Review of 1,497 cases
Author(s) -
Dupont J. Benton,
Lee J. Rillens,
Burton George R.,
Cohn Isidore
Publication year - 1978
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(197803)41:3<941::aid-cncr2820410323>3.0.co;2-m
Subject(s) - medicine , adenocarcinoma , gastrectomy , stomach , survival rate , surgery , carcinoma , cancer , mortality rate , general surgery , stomach cancer , gastroenterology
The records of 1,497 patients with histologically proven adenocarcinoma of the stomach were reviewed from Charity Hospital over the 25‐year period, 1948 to 1973. The operability rate was 82% and the resectability rate was 48%. In this series gastric carcinoma predominated in males and Negroes. Necropsy studies indicate a similar frequency of involvement of various organs in patients not operated upon as well as those subjected to a prior operation, which suggests the need for some therapeutic endeavors aimed at a wider base than the primary organ. The five‐year survival rate, 7.4 overall, varied from 2.0% after esophagogastrectomy to 22.1% after radical subtotal gastrectomy, and to 30.3% for those with localized disease. One hundred one patients survived five years or more, and 5.4% survived ten years or more after the diagnosis of gastric cancer. Radical subtotal gastrectomy gave the best results in this series, whether measured in terms of median survival, five‐year survival, or operative mortality. Esophagogastrectomy and by‐pass procedures had high mortality and low survival rates, and should be reserved for special conditions.