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Proximal tubular dysfunction associated with Burkitt's lymphoma
Author(s) -
Goldsweig Howard G.,
De Champlain MarieLaure Brisson,
Davidman Michael
Publication year - 1978
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(197802)41:2<568::aid-cncr2820410225>3.0.co;2-c
Subject(s) - medicine , glycosuria , aminoaciduria , lymphoma , pathology , infiltration (hvac) , renal injury , kidney , endocrinology , diabetes mellitus , urine , physics , thermodynamics
Abstract Generalized aminoaciduria, uricosuria, glycosuria and phosphaturia were discovered in a patient with advanced Burkitt's lymphoma with renal infiltration. The literature is reviewed and three pathogenetic mechanisms are discussed. It is presumed that proximal tubular dysfunction in this case was related to the marked peritubular infiltrate causing cell mediated immunological injury or direct tubular destruction by tumor.