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Malignant myoepithelioma of the parotid gland
Author(s) -
Crissman John D.,
Wirman John A.,
Harris Anthony
Publication year - 1977
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(197712)40:6<3042::aid-cncr2820400642>3.0.co;2-n
Subject(s) - myoepithelioma , myoepithelial cell , parotid gland , pathology , medicine , salivary gland , cancer , immunohistochemistry
Myoepithelial cells are a significant component of most types of salivary gland neoplasms. A small but increasing number of case reports have also shown that pure myoepitheliomas form a distinct class of neoplasms with unique histological features. Previously reported cases have been either benign or, at most, locally aggressive. We present here a case of a malignant myoepithelioma of the parotid gland, confirmed by electron microscopy, that was locally aggressive and eventually metastasized. Review of this case and of existing reports indicates that myoepitheliomas exhibit a wide range of biological behavior that seems to correlate with their histological appearance. Cancer 40:3042‐3049, 1977.