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Studies on carcinoembryonic antigen levels in patients with adenocarcinoma of the uterus
Author(s) -
Kjorstad Kjell E.,
Orjaseter Harald
Publication year - 1977
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(197712)40:6<2953::aid-cncr2820400630>3.0.co;2-0
Subject(s) - carcinoembryonic antigen , medicine , uterus , adenocarcinoma , gynecology , cancer
Carcinoembryonic antigen was determined before treatment in 101 patients with adenocracinoma of the uterus. If 2.5 ng/ml is accepted as the upper normal value, 34% of the patients with cancer of the corpus had elevated levels. Only 7% had values exceeding 5 ng/ml. The highest recorded value in endometrial carcinoma was 8.5 ng/ml. In adenocarcinoma of the cervix 68% had values over 2.5 ng/ml and a direct correlation between nodal metastases and plasma elevation of CEA was found. The highest recorded value for endocervical cancer was 108 ng/ml. No patient with localized disease had a value over 4.0 ng/ml. It is concluded that adenocarcinomas of the cervix and corpus have different biological properties, and that in adenocarcinoma of the cervix determination of CEA is a reliable indicator of the extent of disease. Cancer 40:2953‐2956, 1977.