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The identification of individuals at high risk for large bowel cancer and the application of preventive measures in their management. Chromosome studies in gardner syndrome and familial polyposis
Author(s) -
Borgaonkar Diagamber S.,
Trips Ludmila,
Krush Anne J.,
Murphy Edmond A.
Publication year - 1977
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(197711)40:5+<2531::aid-cncr2820400920>3.0.co;2-r
Subject(s) - medicine , colorectal cancer , cancer , chromosome , identification (biology) , lynch syndrome , short bowel syndrome , genetics , gene , dna mismatch repair , parenteral nutrition , botany , biology
The significance of chromosomal markers in linkage and assignment has been pointed out. The usefulness of linkage in disease prevention is discussed with the limitations of this approach.