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Primary malignant tumors of the thyroid gland. A clinicopathologic study of 254 cases
Author(s) -
Selzer Golda,
Kahn Leonard B.,
Albertyn Lynda
Publication year - 1977
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(197710)40:4<1501::aid-cncr2820400422>3.0.co;2-x
Subject(s) - medicine , thyroid , papillary carcinoma , multinodular goitre , pathology , follicular carcinoma , follicular phase , thyroiditis , thyroid tumors , carcinoma , thyroid carcinoma , thyroidectomy
Of 254 primary malignant tumors of the thyroid gland diagnosed in the pathology department of the University of Cape Town, 212 (83.5%) were differentiated carcinomas. In this differentiated group, tumors composed exclusively of papillary structures exhibited the most favorable prognosis; local recurrences and/or spread were noted in tumors with a mixed papillary and follicular pattern and, more commonly, in those with a pure follicular pattern. A chronic lymphocytic thyroiditis occurred in association with 21 tumors (8.3%) but an associated multinodular goitre was found in only nine patients (3.5%). In addition to the well‐known preponderance of thyroid carcinoma in women, a majority of lesions occurred in white patients in this series despite a higher hospital admission rate for coloreds (mulattos).