Premium
Endometrial stromal sarcomas
Author(s) -
Yoonessi Mahmood,
Hart William R.
Publication year - 1977
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(197708)40:2<898::aid-cncr2820400246>3.0.co;2-x
Subject(s) - endometrial stromal sarcoma , medicine , sarcoma , stromal cell , anaplasia , endometrial cancer , uterus , pathology , hysterectomy , cancer
This study is a clinicopathologic evaluation of seven patients with endometrial stromal sarcoma of pure homologous type. Histologic distinction from endometrial stromatosis was based on the presence of high mitotic activity and nuclear anaplasia. One sarcoma appeared to have originated from invasive stromatosis. All patients died within 27 months although the tumor was judged to have been confined to the uterus at the time of hysterectomy in five patients. The aggressive clinical behavior and high mortality rate documented in this and other studies indicate that stromal sarcoma should be distinguished from the better differentiated and more indolent endometrial stromal tumor known as stromatosis or endolymphatic stromal myosis. It is suggested that surgery be supplemented by irradiation and/or chemotherapy as primary treatment for stromal sarcoma in view of its dismal prognosis. Cancer 40:898–906, 1977.