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VM 26 and VP 16–213: A comparative analysis
Author(s) -
Rozencweig Marcel,
Von Hoff Daniel D.,
Henney Jane E.,
Muggia Franco M.
Publication year - 1977
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(197707)40:1<334::aid-cncr2820400147>3.0.co;2-x
Subject(s) - medicine , pharmacology
Abstract VM 26 and VP 16–213 are epipodophyllotoxin analogs. This paper presents a comparative analysis of their experimental and clinical features but fails to disclose any significant difference between these drugs. Similar studies with other classes of compounds might help to define some rationale for the development of analogous cytotoxic agents. Cancer 40:334–342, 1977.