Premium
A new histochemical and biochemical approach to olfactory esthesioneuroma. A nasal tumor of neural crest origin
Author(s) -
Micheau Christian
Publication year - 1977
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(197707)40:1<314::aid-cncr2820400144>3.0.co;2-7
Subject(s) - neural crest , medicine , pathology , neuroblastoma , anatomy , biology , microbiology and biotechnology , genetics , embryo , cell culture
A close collaboration between E.N.T. surgeons and pathologists permitted us to obtain 6 cases of olfactory esthesioneuroma in which fresh tumor tissue was available. Histochemical and biochemical studies were made in comparison with neuroblastoma. Different reactions and assays performed revealed a similarity with sympathetic tumors. Moreover, the presence of catecholamines in esthesioneuroma provides a great help in diagnostic as does electron microscope examination. 40:314–318, 1977.