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Mucinous (adenocystic) carcinoma of sweat glands with widespread metastasis: Case report with ultrastructural study
Author(s) -
Yeung KaiYiu,
Stinson James C.
Publication year - 1977
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(197706)39:6<2556::aid-cncr2820390637>3.0.co;2-d
Subject(s) - medicine , pathology , axilla , scalp , mucinous carcinoma , adenocarcinoma , metastasis , ultrastructure , anatomy , cancer , breast cancer
An unusual case of mucinous adenocarcinoma of the sweat glands originating from the right axilla is described. Despite complete control of the primary tumor after local excision, diffuse metastatic lesions continued to appear in the scalp, face, upper and lower extremities, sacral and pelvic bones, and left posterior iliac bone marrow space. The tumors were radioresistant. Multiple trials of various chemotherapeutic regimens, including alkylating agents, antifolates, antipyrimidines, vinca alkaloids, and antineoplastic antibiotics, were ineffective. The cutaneous neoplasms were grossly round, smooth, red, glistening, and cystic and were filled with a gelatinous mucinous material. Microscopic and ultrastructural findings are described.