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Membranous basal cell adenoma of parotid gland, dermal cylindromas, and trichoepitheliomas: Comparative histochemistry and ultrastructure
Author(s) -
Headington John T.,
Batsakis John G.,
Beals Theodore F.,
Campbell Tom E.,
Simmons Jerry L.,
Stone William D.
Publication year - 1977
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(197706)39:6<2460::aid-cncr2820390624>3.0.co;2-6
Subject(s) - pathology , parotid gland , ultrastructure , basal (medicine) , immunohistochemistry , adenoma , medicine , anatomy , biology , insulin
A basal cell adenoma of parotid, eccrine dermal cylindromas and trichoepitheliomas occurring in the same patient were examined by light and electron microscopy and histochemistry. The eccrine and parotid adenomas were similar both structurally and histochemically except for the presence of Langerhans cells in the cutaneous adenoma and well differentiated mucinous cells in the parotid tumor. The three different hamartomas found in this individual may represent the effect of a single pleiotropic gene acting on ontogenetically related stem cells.