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Combination chemotherapy of metastatic malignant schwannoma with vincristine, adriamycin, cyclophosphamide, and imidazole carboxamide. A case report
Author(s) -
Goldman Richard L.,
Jones Stephen E.,
Heusinkveld Robert S.
Publication year - 1977
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(197705)39:5<1955::aid-cncr2820390507>3.0.co;2-f
Subject(s) - medicine , vincristine , cyclophosphamide , chemotherapy , doxorubicin , schwannoma , combination chemotherapy , oncology , radiology
This report describes a patient with a 15‐year history of schwannoma (peripheral nerve sheath sarcoma) who developed extensive pulmonary metastases associated with hypoxemia. Treatment with chemotherapy consisting of cyclophosphamide, vincristine, Adriamycin, and imidazole carboxamide resulted in a complete remission lasting 17+ months. Malignant schwannoma should probably be regarded as a drug sensitive neoplasm.