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Oral fluorouracil therapy of hepatoma
Author(s) -
Kennedy Peter S.,
Lehane Daniel E.,
Smith Frank E.,
Lane Montague
Publication year - 1977
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(197705)39:5<1930::aid-cncr2820390503>3.0.co;2-7
Subject(s) - medicine , fluorouracil , regimen , gastroenterology , oncology , surgery , chemotherapy
Oral fluorouracil was administered weekly to 12 consecutive patients with unresectable hepatoma. Six patients showed an objective response with a significant increase in survival duration compared to nonresponders and to untreated patients. The clinical features of these cases are discussed, along with details of therapy, and possible reasons for the encouraging results noted with this treatment regimen.