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A comparison of Hodgkin's disease in Alameda County, California, and Connecticut. Histologic subtype and age distribution
Author(s) -
Silverman Debra T.,
Correa Pelayo,
O'Conor Gregory T.,
Myers Max H.,
Axtell Lillian M.,
Bragg Kay U.
Publication year - 1977
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(197704)39:4<1758::aid-cncr2820390457>3.0.co;2-e
Subject(s) - medicine , disease , incidence (geometry) , cancer , socioeconomic status , gerontology , demography , pathology , environmental health , population , physics , sociology , optics
A comparison of the histologic patterns of Hodgkin's disease in Alameda County, California and Connecticut was made in relation to age. All Hodgkin's disease cases from the Alameda County Cancer Registry diagnosed between 1960 and 1969 for which adequate material was available for evaluation were reviewed and histologically subtyped according to the Rye classification (159 cases). The age‐specific relative frequencies and incidence rates for the histologic subtypes of Hodgkin's disease in Alameda County were estimated and compared to those estimated for Hodgkin's disease in Connecticut. The morphologic expression of Hodgkin's disease in both areas was similar and characteristic of economically developed regions with high living standards. The comparison supports the hypothesis that the host immune capacity, influenced by socioeconomic factors, has a strong and measurable effect on the pathogenesis of Hodgkin's disease.