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Hypophysectomy in the treatment of disseminated prostate carcinoma
Author(s) -
Silverberg Gerald D.
Publication year - 1977
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(197704)39:4<1727::aid-cncr2820390451>3.0.co;2-1
Subject(s) - medicine , hypophysectomy , prostate , prostate cancer , carcinoma , surgery , oncology , cancer , hormone
Seventeen patients suffering severe pain secondary to disseminated prostate cancer were subjected to hypophysectomy. Prolonged remission of pain and increased survival duration appeared to be consequent to obtaining objective signs of tumor regression. Patients who had only subjective improvement had significantly shorter periods of remission and survival. Patients with hemato‐crits less than 30% and patients demonstrating evidence of liver involvement did not obtain objective remissions.