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High dose irradiation to biopsy confirmed aortic node metastases from carcinoma of the uterine cervix
Author(s) -
Piver M. Steven,
Barlow Joseph J.
Publication year - 1977
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(197703)39:3<1243::aid-cncr2820390333>3.0.co;2-t
Subject(s) - medicine , cervix , pelvis , biopsy , cervical cancer , radiology , radiation therapy , carcinoma , uterus , cancer , surgery
Twenty‐one women with biopsy proven aortic node metastases from previously untreated carcinoma of the uterine cervix were treated with high dose irradiation to the pelvis and para‐aortic areas. The majority received 6000 rads to the pelvis and para‐aortic nodes by split course therapy plus 2500 rads by intracavitary radium to point A; 57.1% sustained severe complications to the stomach, small intestine or colon. Only 14.2% are surviving over 2 years free of recurrence. Though approximately 40% of women with Stages III and IV cervical cancer will have metastases to the para‐aortic nodes, to date there is no satisfactory therapy that results in a significant number of such women surviving free of recurrent cervical cancer.