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Advances in the staging and treatment of ovarian cancer
Author(s) -
Fisher Richard I.,
Young Robert C.
Publication year - 1977
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(197702)39:2+<967::aid-cncr2820390736>3.0.co;2-g
Subject(s) - medicine , occult , anaplasia , ovarian cancer , chemotherapy , disease , oncology , cancer , abdomen , radiology , surgery , pathology , alternative medicine
The age adjusted death rate for ovarian cancer has remained unchanged for the past 20 years. Recent data obtained by staging ovarian cancer patients with lymphangiography and peritoneoscopy demonstrated that many patients with apparently localized disease actually have occult dissemination within the abdomen. These new staging techniques plus the determination of the histologic grade of anaplasia may permit a more precise determination of a patient's prognosis and therefore better design of therapeutic stategy. Radiotherapeutic techniques are being adapted to attempt to treat some areas of occult disease. Numerous single chemotherapeutic agents are capable of producing objective tumor responses. Preliminary data suggest that combination chemotherapy can increase the objective response rate above that seen with single agents. Longer follow‐up is necessary to determine whether combination chemotherapy can prolong survival.