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Extreme thrombocytosis associated with malignancy
Author(s) -
Spigel Stuart C.,
Mooney Lewis R.
Publication year - 1977
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(197701)39:1<339::aid-cncr2820390150>3.0.co;2-t
Subject(s) - thrombocytosis , medicine , thrombopoiesis , malignancy , platelet , adenocarcinoma of the lung , adenocarcinoma , lesion , pathology , gastroenterology , cancer , haematopoiesis , stem cell , biology , megakaryocyte , genetics
A case is described in which a platelet count of 6,000,000/mm 3 occurred in association with adenocarcinoma of the lung and remitted following definitive radiotherapy of the primary lesion. Despite the magnitude of the platelet elevation, thrombohemorrhagic phenomena were not observed. Extreme thrombocytosis of this magnitude is rare in either primary or secondary disorders of thrombopoiesis. The occurrence of unexplained thrombocytosis demands the exclusion of malignancy.